Preheat oven to 375 degrees F. Line a baking sheet with parchment paper, set aside.
Season both sides of halved chicken breasts with salt and pepper.
In the first shallow dish, place flour.
In the second shallow dish, whisk together eggs, hot sauce, garlic powder, and onion powder.
In the third shallow dish, combine panko and parmesan.
Dip chicken into flour. Shake to remove any excess. Dip into the egg mixture. Then press into the panko and parmesan mixture. Make sure the chicken is fully coated in panko. Repeat with remaining chicken and set aside on a plate.
Heat avocado oil in a skillet over medium heat. Add 2 to 3 pieces of chicken to the skillet. Don't crowd the skillet. Brown chicken on each side, 1-2 minutes. Transfer to prepared baking sheet. Repeat with remaining chicken. Add more oil as needed to crisp up the chicken.
Bake for 18-22 minutes or until chicken is cooked through.
While chicken is baking, make the sauce. In a small saucepan, gently heat the honey, hot sauce, cayenne, chili powder, garlic powder, salt and pepper. Drizzle the hot honey sauce over the chicken when it comes out of the oven and serve immediately.