Preheat oven to 450 F.
In a large bowl, combine the ground chicken, garlic powder, onion powder, salt, pepper, and hot sauce. Mix until evenly combined. Set aside.
Lay out a large parchment paper on a clean surface. Sprinkle parchment with 2-3 tablespoons of flour. Place the chicken mixture on top. Coat your hand with a little flour and press the chicken into a large rectangle or oval shape. Continue flattening until it's about ¼ inch thick.
Brush the top with half of the beaten egg mixture. Cover generously with half of the panko and press lightly so it can adhere. Spray with oil.
Place another sheet of parchment over the top. Fold the edges of the parchment paper to seal. Carefully and quickly flip the cutlet. Remove the top parchment. If this seems a little intimidating to you, try this method. Slide a large cutting board under the parchment paper. Lightly oil a baking sheet and place upside down onto the chicken cutlet. (The oiled part should be on the same side of the chicken cutlet). Slide one hand under the cutting board and the other on top of the baking sheet. Hold them tightly together and perform a flip. Remove the cutting board and discard the parchment paper.
Brush with remaining egg, cover with remaining panko, and spray generously with oil.
Bake for 14–18 minutes, until golden and crispy. If needed, broil for 1–2 minutes at the end for extra crunch.
Make the hot honey while the cutlet bakes. In a small saucepan, gently heat the honey, hot sauce, cayenne, chili powder, garlic powder, salt and pepper. Drizzle the hot honey sauce over the chicken when it comes out of the oven, slice, and serve immediately.